Most of the researchers of HEROES project attended the third T21RS International conference in Barcelona. The meeting provided an invaluable opportunity to present and discuss the initial results of the project to the Down syndrome research community. Several posters and short talks were presented (see below). HEROES consortium is excited to present the final results of the project in the next T21RS conference in 2021!
Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene-dose-sensitive AD-suppressor in human brain. A. Murray et al (Partner 3)
Investigating the role of the locus coeruleus as an indicator of early neurodegenerative change in TgDyrk1A mice. M. Fructuoso et al (Partner 2)
Noradrenergic dysfunction in mBACtgDyrk1a mice. JL. Musoles et al (Partner 1)
The role of genes other than APPin Alzheimer’s disease development F. Wiseman et al (Partner 3)